Pharmaceutical, Foods and Cosmetic Industries

Thermal Analysis is a powerful set of methods for the characterization of pure substances and blends. Used either in complement with or as a supplement to classical techniques employed in chemical laboratories such as spectroscopical methods, chromatography or X-ray structure analysis, Thermal Analysis yields valuable information about the physical-chemical properties of materials. Typical areas of application are purity studies, the determination of melting or glass transition temperatures, polymorphism studies, the determination of phase diagrams, studies of interaction between components, the determination of thermal stabilities, the analysis of composites, and the study of decomposition kinetics. This makes Thermal Analysis to a versatile problem-solving tool in research & development, quality assurance and process optimization.


The Methods:

The methods most often used in the areas of pharmaceuticals, cosmetics and foods are DSC (Differential Scanning Calorimetry), TG (Thermogravimetry) and DMA (Dynamic-Mechanical Analysis).

A DSC measures the change in thermal efficiency (heat absorption or loss) of a sample during heating or cooling as compared to an inert reference. With a thermobalance (TG), the mass change of a sample as a function of temperature or time can be determined. The DMA yields modulus values (storage modulus, loss modulus, loss factor) and draws conclusions about the visco-elastic behavior of materials.


Our Solution:

NETZSCH Analyzing & Testing offers you complete solution packages for your needs, consisting of hardware, software, comprehensive services and expert support – while fully conforming to regulations such as GMP, GLP or 21 CFR Part 11.


Please select:

• Pharmaceuticals

Our product recommendation for you:

DSC 204 F1 Phoenix®
Very high sensitivity and resolution can be realized with this premium Differential Scanning Calorimeter (DSC), which also features an automatic sample changer (ASC), temperature modulation (TM-DSC), baseline optimization (BeFlat®), correction of thermal resistance and time constants (DSC-correction), even coupling to QMS and FTIR as well as UV-extension for photo-calorimetry.
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Photo-DSC 204 F1 Phoenix®
The Photo-DSC 204 F1 Phoenix®, Differential Scanning Calorimeter, is our answer to the market trend seeking solutions for analyzing the UV curing of light-activated resin systems, adhesives, paints, coatings and dental masses. Further application areas include determining the effect of light on the shelf life of foods or technical oils, fats and lubricants.
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TG 209 F3 Tarsus
This easy-to-use thermo-microbalance (TGA) was developed especially for routine applications in the field of plastics, but also for the chemical industry. It is the ideal starter unit up to 1000°C and, together with the DSC 200 F3 Maia®, represents a cost-effective overall concept.
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TG 209 F1 Iris®
This premium thermobalance (TGA), through flexibility in the fittings, covers all imaginable applications of a modern TGA in the range up to 1000°C. High sensitivity, short cooling times and the automatic sample changer (ASC), make this TGA particularly well-suited for the compositional analysis of plastics and rubbers.
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NEW: STA 449 F1 Jupiter®
With the introduction of the new STA 449 F1 Jupiter® NETZSCH is setting new standards. Unlimited configuration flexibility and unmatched performance are the foundations for a great variety of application possibilities in the fields of ceramics, metals, plastics, and composites over a broad temperature range (-150...2400°C).
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DMA 242 C
The robust construction of the DMA 242 C and the high resolution of the deformation measuring system enable precise measurements on both very rigid and very soft samples. The most varied of deformation types, digital signal filtering, kinetic evaluation and frequency extrapolation make the DMA 242 C to a real all-rounder.
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QMS 403 C Aëolos®
The QMS 403 Aëolos® is a very compact mass spectrometer with a heated capillary inlet system, specially designed for routine analysis of volatile decomposition products of thermal analysis (instrument for EGA: Evolved Gas Analysis).
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FTIR Coupling
Different thermo-analysis systems can be combined with a Fourier Transform-Infrared Spectrometer (FTIR), which has proved its efficiency especially in the organic field. (EGA method: Evolved Gas Analysis)
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APTAC 264
APTAC 264 is capable of studying exothermic reactions at temperatures from ambient to 500ºC and pressures ranging from vacuum to 140 bar (2,000 psia). As a calorimeter, APTAC 264 can detect and track exotherms at heat generation rates ranging from 0.04 K/min to 400 K/min.
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Accelerating Rate Calorimeter 244 (ARC®)
The cost-effective Accelerating Rate Calorimeter 244 (ARC® 244) is designed to safely measure the amount and rate of heat release associated with the processing or storage of chemicals with a sample volume of 0.5 ml to 7 ml. The key features are high performance, safety, usability, and flexibility with data integrity and robustness in a temperature range from ambient to 500°C.
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Accelerating Rate Calorimeter 254 (ARC®)
This new Accelerating Rate Calorimeter (model ARC® 254), formerly known as TIAX New ARC 5000, is a specialized instrument to help industry operate safely and profitably. Highly versatile, miniature chemical reactor, it measures the thermal and pressure properties of exothermic chemical reactions. The resulting information helps engineers and scientists identify potential hazards and tackle key elements of process optimization and thermal stability.
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NEW: MMC 274 Nexus™
The MMC 274 Nexus™ can be used in conjunction with the DSC and the Accelerating Rate Calorimeter where its special features better match the application. The MMC 274 Nexus™ is used for measuring heats of reaction, reaction rates, endotherms, heat capacities, phase changes, gas generation rates and vapor pressures.
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