Good Stability Versus Good Tabletability

Good Stability Versus Good Tabletability: The Choice of Modification

Many pharmaceutical solids exhibit polymorphism, i.e., the ability of a substance to exist in different crystalline forms. The polymorphic form can have significant influence on pharmaceutical processing and can, for example, affect grinding, granulation and tabletability. A DSC measurement allows for the characterization of the present modification. Here, different modifications of paracetamol are distinguished by means of DSC.

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How to use TGA for the quality control of carbon fiber-reinforced polymers

The determination of fiber volume fraction is crucial for the quality control of carbon fiber-reinforced polymers (CFRP) in order to ensure their favorable mechanical and physical properties for the use in aerospace, wind energy and automotive sectors. A new thermogravimetric testing method, published by Dominik Grund in the journal “Polymer Testing”, considers heating rate, analysis atmosphere and sample size to efficiently ensure high quality of the material. This editorial summarizes the steps for the use of TGA in the quality control of carbon fiber-reinforced polymers.

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A phase diagram portrays the equilibrium conditions between the thermodynamically separated phases or it shows which phases are present in the material system at different temperatures, pressures and compositions.

How DSC Measurements help with Phase Diagrams

A phase diagram portrays the equilibrium conditions between the thermodynamically separated phases or it shows which phases are present in the material system at different temperatures, pressures and compositions. 

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Featured NETZSCH Instruments

HFM 446 Lambda Series

The new HFM 446 Lambda Series features a standardized method for the measurement of thermal conductivity which is equally applicable in research and development and in quality assurance.

DSC 204 F1 Phoenix®

Con questo DSC (Calorimetro Differenziale a Scansione) all’avanguardia si possono ottenere elevatissime sensibilità e risoluzione. Inoltre si possono avere come accessori un autocampionatore (ASC), temperatura modulata (TM-DSC), ottimizzazione della line di base (BeFlat®), correzione delle resistenza termica e della costante di tempo (DSC-correction) accoppiamento a QMS e FTIR, estensione UV per foto-calorimetria.

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