In this webinar, Dr. Sanjeeva Murthy from Rutgers University is talking about the following topic:
Polymers are now widely used for tissue repair and replacement in the form of implantable biomedical scaffolds. Examples include surgical meshes, cardiovascular stents, nerve conduits, and bone regeneration scaffolds and fixation devices. Thermal processing is a common denominator in all these applications. Rather than discuss the use of the rheometer to study polymer rheology, on which a large body of literature exist, the webinar will focus on its use as a tool for optimizing the process parameters with a few grams of polymer before sacrificing hundreds of grams in an extruder. The capillary rheometer is indispensable in the evaluation of degradable polymers that have a tight window for processing. We have taken advantage of the temperature control and precision of the rheometer to assess the thermal stability of polymers, processing aids, and the API compounded in the polymers.
The capillary rheometer can be used as a small-scale extruder to screen a large number of polymers by extruding ~ 100µm diameter fibers from which their mechanical and degradation behavior can be ascertained. We have also used rheology to referee the molecular weight determinations of a series of polymers. Some examples of recent successes using the rheometer in our laboratory are, the optimization of the conditions for extrusion of fibers from our tyrosine-derived polymers, extrusion of ~ 5 mm rods for machining into bone fixation screws, evaluation polymers for 3D printing applications, and extruding the 1.75 mm diameter filaments used with 3D printers that run on fusion deposition modeling technology.
Sanjeeva Murthy is an Associate Research Professor at the Laboratory for Biomaterials Research (LBR), Department of Chemistry and Chemical Biology, Rutgers University. He is a Material Scientist with expertise in polymers, biomaterials and biological structures. LBR's focus is the development of polymeric materials, characterizing them, and fabricating them into devices, scaffolds for tissue repair and replacement, and biomedical implants. Melt processing and understanding factor that influence melt behavior of polymers being integral part of these activities.